DoxyPEP may be appropriate for sexually active individuals at higher risk of bacterial STIs, including those with a prior STI diagnosis, inconsistent condom use, or multiple partners.
It’s also commonly considered by individuals already taking HIV PrEP who want additional protection against bacterial infections. DoxyPEP isn’t appropriate for everyone, so a provider review of your health history is an important first step.
DoxyPEP is an emerging, highly effective strategy for reducing the risk of certain bacterial STIs after potential exposure, including chlamydia, gonorrhea, and syphilis.
Taken as a single dose within 72 hours of unprotected contact, clinical trials have shown it can meaningfully reduce bacterial STI risk in high-risk individuals.
It works best as one part of a broader sexual health strategy that includes regular testing and, when appropriate, condom use.
Coverage for DoxyPEP consultations and prescriptions varies by insurance plan.
We recommend confirming your prescription drug benefits with your insurance provider, and self-pay pricing is available as well.
DoxyPEP is a single dose of the antibiotic doxycycline taken within 72 hours of unprotected sexual contact to help reduce the risk of certain bacterial STIs.
Clinical trials have shown DoxyPEP can reduce the risk of bacterial STIs, including chlamydia, gonorrhea, and syphilis, by a significant margin in high-risk individuals.
DoxyPEP may be appropriate for sexually active individuals at higher risk of bacterial STIs. Your provider will review your health history to confirm it’s right for you.
DoxyPEP should not be taken more than once every 24 hours. Your provider will give you specific guidance based on your situation.
No. DoxyPEP is not a replacement for regular STI testing or condom use. It’s meant to be used alongside other prevention strategies.
Coverage varies by plan. We recommend checking your prescription benefits with your insurance provider before your visit.
